Claudette Colbert

Cleopatra

Warren William

Julius Caesar

Henry Wilcoxon

Marc Antony

Joseph Schildkraut

King Herod

Ian Keith

Octavian

Gertrude Michael

Calpurnia

C. Aubrey Smith

Enobarbus

Irving Pichel

Apollodorus

Arthur Hohl

Brutus

Edwin Maxwell

Casca

Leonard Mudie

Pothinos

Ferdinand Gottschalk

Glabrio (scenes deleted)

Claudia Dell

Octavia

Harry Beresford

Soothsayer

Jayne Regan

Lady Vesta

William Farnum

Lepidus

Lionel Belmore

Fidius

Florence Roberts

Lady Flora

Richard Alexander

General Philodemas

William V. Mong

Court Physician