Bryan Cranston

Chief (voice)

Koyu Rankin

Atari Kobayashi (voice)

Bob Balaban

King (voice)

Edward Norton

Rex (voice)

Bill Murray

Boss (voice)

Jeff Goldblum

Duke (voice)

Kunichi Nomura

Mayor Kobayashi (voice)

Fisher Stevens

Scrap (voice)

Akira Takayama

Major Domo (voice)

Greta Gerwig

Tracy Walker (voice)

Ken Watanabe

Head Surgeon (voice)

Frances McDormand

Interpreter Nelson (voice)

Nijiro Murakami

Editor Hiroshi (voice)

Harvey Keitel

Gondo (voice)

Liev Schreiber

Spots (voice)

Scarlett Johansson

Nutmeg (voice)

Tilda Swinton

Oracle (voice)

F. Murray Abraham

Jupiter (voice)

Courtney B. Vance

Narrator (voice)

Yoko Ono

Assistant-Scientist Yoko-ono (voice)