Pat O’Brien

Knute Rockne

Gale Page

Bonnie Skiles Rockne

Ronald Reagan

George Gipp

Donald Crisp

Father John Callahan, C.S.C

Albert Bassermann

Father Julius Nieuwland

John Litel

Committee Chairman

Henry O'Neill

Doctor

Owen Davis Jr.

Gus Dorais

John Qualen

Lars Knutson Rockne

Dorothy Tree

Martha Rockne

Johnny Sheffield

Knute - Age 7

Kane Richmond

Elmer Laydon - One of The Four Horsemn

William Marshall

Don Miller - One of The Four Horsemen

Howard Jones

USC Coach Howard Jones

Erville Alderson

Kansas Farmer Witnessing Airplane Crash (uncredited)

Rudolph Anders

Elder in Norway (uncredited)

Wade Boteler

Trainer (uncredited)

Egon Brecher

Elder in Norway (uncredited)

David Bruce

Reporter When Knute is Ill (uncredited)

Cliff Clark

Danny - Post Office Paymaster (uncredited)