Patrick Dempsey

Kenai (voice)

Mandy Moore

Nita (voice)

Jeremy Suarez

Koda (voice)

Rick Moranis

Rutt (voice)

Dave Thomas

Tuke (voice)

Andrea Martin

Anda (voice)

Catherine O'Hara

Kata (voice)

Wanda Sykes

Innoko (voice)

Wendie Malick

Aunt Siqiniq (voice)

Kathy Najimy

Aunt Taqqiq (voice)

Michael Clarke Duncan

Tug (voice)

Jim Cummings

Bering / Chilkoot (voice)

Jeff Bennett

Additional Voices (voice)

Jessie Flower

Additional Voices (voice)

Tress MacNeille

Additional Voices (voice)