Steve Carell

Gru / Dru (voice)

Kristen Wiig

Lucy Wilde (voice)

Trey Parker

Balthazar Bratt (voice)

Miranda Cosgrove

Margo (voice)

Dana Gaier

Edith (voice)

Nev Scharrel

Agnes (voice)

Steve Coogan

Fritz / Silas Ramsbottom (voice)

Julie Andrews

Gru’s Mom (voice)

Jenny Slate

Valerie Da Vinci (voice)

Pierre Coffin

Mel / Minions / Museum Director / Additional Voices (voice)

Chris Renaud

Additional Minions (voice)

Andy Nyman

Clive the Robot (voice)

Michael Beattie

The Scar Faced Man / TMZ Announcer (voice)

Adrian Ciscato

Niko (voice)

Brian T. Delaney

Commercial Announcer / Military Officer / Additional Voice (voice)

Ken Daurio

Celebrity (voice)

Lori Alan

Additional Voices (voice)

Carlos Alazraqui

Additional Voices (voice)

Kyle Balda

Additional Voices (voice)

Teresa Ganzel

Additional Voices (voice)